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If you are ill, you want a medicine to get well again. Before we can give that medicine to you, we research the exact effects on laboratory-grown cells. The most used method for this is a petri dish, where we grow one layer of cells to which we can add the medicine. But you are not a petri dish. Because of this, we cannot research accurately how medicine works in the human body. This can have the consequence that for some patients, medicines do not work well. Therefore, we need more relevant methods to grow cells, to mimic illness in a better way. In the laboratory, I develop miniature systems in which we can grow cells three-dimensionally in a little chamber, like you can see here. Via channels that connect to chamber, we expose the cells to a controlled flow of medicine, like it happens in your body. Eventually, we want to understand how different kinds of medicine work in an environment that is comparable to the human body. And with that, how you will react to medicine.

A MINIATURE BODY IN A LAB
ANIKA NAGELKERKEPROFILE
University of Groningen

If you are ill, you want a medicine to get well again. Before we can give that medicine to you, we research the exact effects on laboratory-grown cells. The most used method for this is a petri dish, where we grow one layer of cells to which we can add the medicine. But you are not a petri dish. Therefore, we need more relevant methods to grow cells, to mimic illness in a better way.

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